That is an open access article distributed under the Creative Commons Attribution Accredit , which permits unrestricted use, distribution, and look-alike in any medium, provided the original work is properly cited. Stem cubicle SC therapy for erectile dysfunction ED has old-fashioned investigated in 35 published studies, with one being a small-scale clinical go. Transplantation of SCs was done mostly by intracavernous IC injection, as seen in 25 studies.
Allogeneic and xenogeneic transplantations procure increasingly been performed but their immune-incompatibility issues were rarely discussed. More late-model studies also tend to use combinatory therapies at near modifying or supplementing SCs with angiogenic or neurotrophic genes or proteins. But still, few studies absolutely investigated and none proved paracrine action as a therapeutic mechanism.
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